Some basic concepts-
Erwin Chargaff found:
1) Composition of DNA varied from one species to another- bases= A, C, T, G
2) A=T (straight edge letters)
C=G (curved letters)
The base pairs (A to T, and C to G) are held together by hydrogen bonds
C and T are pyrimindines
G an A are purines
The nucleotide is made up of phosphate, sugar and a base.
The phosphodiester is the bond between the sugar and phosphate.
The structure has two ends
1) phosphate= 5 prime
2) sugar=3 prime (3 carbon)
The sugar molecule has an OH attached to it. It only recognizes it because it is polar (negative).
It is a little hard to explain, so here is a picture of what I am talking about.
In class, we also made our own paper DNA structures.
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